Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs738409
rs738409
0.100 GeneticVariation BEFREE Metabolic syndrome (MetS) and genetic polymorphisms PNPLA3 rs738409, TM6SF2 rs58542926 and MBOAT7 rs641738 are known inductors of non-alcoholic fatty liver disease (NAFLD). 31851849

2019

dbSNP: rs58542926
rs58542926
0.030 GeneticVariation BEFREE Metabolic syndrome (MetS) and genetic polymorphisms PNPLA3 rs738409, TM6SF2 rs58542926 and MBOAT7 rs641738 are known inductors of non-alcoholic fatty liver disease (NAFLD). 31851849

2019

dbSNP: rs641738
rs641738
0.010 GeneticVariation BEFREE Metabolic syndrome (MetS) and genetic polymorphisms PNPLA3 rs738409, TM6SF2 rs58542926 and MBOAT7 rs641738 are known inductors of non-alcoholic fatty liver disease (NAFLD). 31851849

2019

dbSNP: rs8192284
rs8192284
0.020 GeneticVariation BEFREE Our results indicate that rs12083537 and rs8192284 in the IL6R gene might be related to the risk of IS in MetS patients. 31836512

2020

dbSNP: rs12083537
rs12083537
0.010 GeneticVariation BEFREE Our results indicate that rs12083537 and rs8192284 in the IL6R gene might be related to the risk of IS in MetS patients. 31836512

2020

dbSNP: rs738409
rs738409
0.100 GeneticVariation BEFREE PNPLA3 I148M is associated with increased risk of prediabetes, metabolic syndrome and insulin resistance in obese patients with NAFLD. 31826069

2019

dbSNP: rs750359414
rs750359414
0.010 GeneticVariation BEFREE These findings propose that the RETN +62G>A polymorphism has a great impact on the circulating resistin concentrations, and that resistin levels are strongly related to MS. 31820685

2019

dbSNP: rs2010963
rs2010963
0.010 GeneticVariation BEFREE Interaction between Vascular Endothelial Growth Factor-A (rs2010963) Gene Polymorphisms and Dietary Diversity Score on Cardiovascular Risk Factors in Patients with Metabolic Syndrome. 31786572

2020

dbSNP: rs8192678
rs8192678
0.040 GeneticVariation BEFREE Meta-analysis demonstrates Gly482Ser variant of PPARGC1A is associated with components of metabolic syndrome within Asian populations. 31678594

2020

dbSNP: rs4994
rs4994
0.100 GeneticVariation BEFREE Adrenergic receptor beta-3 rs4994 (T>C) and liver X receptor alpha rs12221497 (G>A) polymorphism in Pakistanis with metabolic syndrome. 31670283

2019

dbSNP: rs12221497
rs12221497
0.020 GeneticVariation BEFREE Adrenergic receptor beta-3 rs4994 (T>C) and liver X receptor alpha rs12221497 (G>A) polymorphism in Pakistanis with metabolic syndrome. 31670283

2019

dbSNP: rs6688832
rs6688832
0.020 GeneticVariation BEFREE The relationship of <i>HSD11B1</i> rs45487298 and <i>H6PD</i> rs6688832 polymorphisms with obesity and MetS was studied. 31558916

2019

dbSNP: rs45487298
rs45487298
0.010 GeneticVariation BEFREE The relationship of <i>HSD11B1</i> rs45487298 and <i>H6PD</i> rs6688832 polymorphisms with obesity and MetS was studied. 31558916

2019

dbSNP: rs10845640
rs10845640
0.010 GeneticVariation BEFREE Four genetic variants (APOA5_rs651821, EFCAB4B_rs4766165, ZNF259_rs2160669 and APOBEC1_rs10845640) were selected because they increased MetS risk after adjusting for covariates. 31544728

2019

dbSNP: rs2160669
rs2160669
0.010 GeneticVariation BEFREE Four genetic variants (APOA5_rs651821, EFCAB4B_rs4766165, ZNF259_rs2160669 and APOBEC1_rs10845640) were selected because they increased MetS risk after adjusting for covariates. 31544728

2019

dbSNP: rs28665122
rs28665122
0.010 GeneticVariation BEFREE In summary, the results of this study does not indicate significant differences in the SEPP1 (rs7579, rs3877899) and SEPS1 (rs4965373, rs28665122) genotypes between MetS and non-MetS subjects. 31542866

2019

dbSNP: rs3877899
rs3877899
0.010 GeneticVariation BEFREE The mean of SePP in MetS subjects with SEPP1 (rs3877899) GG genotype is significantly lower than the non-MetS g</span>roup (40.73 ± 8.44 vs.83.91 ± 21.33, P = 0.002). 31542866

2019

dbSNP: rs4965373
rs4965373
0.010 GeneticVariation BEFREE The mean of SelS in MetS subjects with SEPS1 (rs4965373) GG genotype is significantly lower than the non-MetS group (4496.99 ± 3688.5 vs. 6148.6 ± 1127.0, P = 0.009). 31542866

2019

dbSNP: rs7579
rs7579
0.010 GeneticVariation BEFREE In summary, the results of this study does not indicate significant differences in the SEPP1 (rs7579, rs3877899) and SEPS1 (rs4965373, rs28665122) genotypes between MetS and non-MetS subjects. 31542866

2019

dbSNP: rs17782313
rs17782313
0.050 GeneticVariation BEFREE However, no association was observed for metabolic variables other than components of MetS across genotypes of both BDNF rs6265 and MC4R rs17782313. 31502573

2019

dbSNP: rs6265
rs6265
0.040 GeneticVariation BEFREE However, no association was observed for metabolic variables other than components of MetS across genotypes of both BDNF rs6265 and MC4R rs17782313. 31502573

2019

dbSNP: rs1800775
rs1800775
0.020 GeneticVariation BEFREE We discovered two variants within/near the <i>CETP</i> gene-rs1800775 and rs3816117-associated with MetS at genome-wide significance level during replication phase in Indians. 31366177

2019

dbSNP: rs3816117
rs3816117
0.010 GeneticVariation BEFREE We discovered two variants within/near the <i>CETP</i> gene-rs1800775 and rs3816117-associated with MetS at genome-wide significance level during replication phase in Indians. 31366177

2019

dbSNP: rs174547
rs174547
0.020 GeneticVariation BEFREE Multiple logistic regression analyses revealed that vegetarians with TT genotype of rs174547 in <i>FADS1</i> gene had higher odds for MetS, larger WC, higher BP, and a lower level of HDL-c. Two-way ANOVA analysis showed that LA interacts with rs174547 in <i>FADS1</i> gene to affect HDL-c (<i>p</i> < 0.05) among vegetarians. 31340443

2019

dbSNP: rs4880
rs4880
0.010 GeneticVariation BEFREE Thus, we investigated the relationship between MnSOD Ala16Val SNP with epilepsy and its influence on MetS, inflammation, apoptosis and DNA damage parameters. 31212050

2019